Reference data

Tesamorelin molecular data

Identity data for tesamorelin, cross-checked between PubChem, UniProt and the FDA prescribing information. Each value links to its source.

Name: Tesamorelin
Classification: Synthetic analogue of human growth hormone-releasing factor (GRF/GHRH)^[3]
Development code: TH9507
Molecular formula (free base): C221H366N72O67S^[1]
Drug substance: C221H366N72O67S · x C2H4O2 (acetate salt, x ≈ 7, per label Section 11)^[3]
Molecular weight: 5135.9 Da (free base, FDA label); 5136 g/mol (PubChem)^[3,1]
CAS Registry Number: 218949-48-5^[1]
PubChem CID: 16137828
UNII: MQG94M5EEO
ATC code: H01AC06
ChEBI: CHEBI:63626
Length: 44 amino acids
N-terminal modification: (3E)-hex-3-enoyl (trans-3-hexenoyl) group on the N-terminal tyrosine^[3,1]
C-terminus: Leucine amide (–NH2)^[2]
Physical form (approved product): Lyophilized powder (white to off-white, per the EGRIFTA WR label)^[3]

Amino-acid sequence

Residues 1–44 of human GHRH (UniProt P01286, peptide 32–75), with the hexenoyl group on Tyr-1 and a C-terminal leucine amide^[2,3].

(3E)-hex-3-enoyl-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2

1.PubChem Compound Summary for CID 16137828, Tesamorelin. National Center for Biotechnology Information. PubChem · accessed 2026-11-11
2.UniProtKB P01286. Somatoliberin (GHRH), Homo sapiens. UniProt · accessed 2026-11-11
3.EGRIFTA WR (tesamorelin) for injection, Prescribing Information. Revised 03/2025; DailyMed SPL version 2 (published 2026-08-03). DailyMed · accessed 2026-11-11